Biomarkers predict response to checkpoint inhibitors in PML
Researchers at Hannover Medical School (MHH) have identified biomarkers that can predict which patients with progressive multifocal leukoencephalopathy (PML) will benefit from therapy with immune checkpoint inhibitors (ICI). The results were published in the journal...
Software: ovrlpy detects hidden sources of error in spatial transcriptomics
In an international collaboration, the Berlin Institute of Health at Charité (BIH) has developed the software tool ovrlpy, which significantly improves the accuracy of spatial transcriptomics analyses. The results were published in the journal Nature Biotechnology...
Metastases: Study from Regensburg and Erlangen refutes old assumption
Metastases have long been considered localized offshoots of a primary tumor that settle in a new organ and only continue to grow there without forming new metastases themselves. A recent study by the Clinic and Polyclinic for Internal Medicine III of the University...
New biomarkers could enable earlier diagnosis of osteoarthritis
Researchers have used advanced spatial mass spectrometry imaging (MALDI-MSI) and proteomics of synovial fluid to demonstrate early molecular remodeling processes in subchondral bone in knee osteoarthritis (OA). These changes are already occurring under intact...
Platelet researcher Dr. Sarah Beck receives Frank Misselwitz Memorial Award
Dr. Sarah Beck from the Department of Experimental Biomedicine I at the University Hospital Würzburg has been awarded the Frank Misselwitz Memorial Award for Excellence in Thrombosis Research by the Bayer Foundation. The one-time prize is endowed with 20,000 euros and...
Psychotherapy: National Association of Statutory Health Insurance Funds plans blanket fee reduction of ten percent
The professional association unith e.V. warns of an imminent blanket reduction of fees for psychotherapeutic services by ten percent. According to media reports, the National Association of Statutory Health Insurance Funds is pushing for a corresponding reduction,...
Organ donation numbers in Germany will reach highest level since 2012 in 2025
In 2025, organ donation numbers in Germany reached their highest level since 2012. A total of 985 people donated organs after their death - 32 more than in 2024 and an increase of 3.4 percent. This corresponds to 11.8 donors per million inhabitants. Through the...
Palforzia end: Children worldwide soon without oral immunotherapy for peanut allergy
The manufacturer Stallergenes Greer has announced the worldwide discontinuation of the distribution of Palforzia. The preparation for oral immunotherapy for peanut allergy will soon no longer be sold. With the market withdrawal, the only approved drug treatment option...
Children’s Hospice Day: Massive undersupply of families with seriously ill children
On the occasion of the nationwide Day of Children's Hospice Work on 10 February, the German Children's Hospice Services are drawing attention to the dramatic undersupply of outpatient and inpatient children's hospice services. A study by the Humboldt University of...
Study: Sound Art for Stress Reduction and Bonding Promotion in High-Risk Pregnancies
A new multicenter research project investigates the effectiveness of art and music therapy in pregnant women with medical complications. The aim is to reduce maternal stress during inpatient stays and to strengthen the prenatal bond between mother and child. The...
