AOK Institute sees savings potential through mandatory biosimilar exchange
The Scientific Institute of the AOK (WIdO) sees potential savings of up to 2.33 billion euros annually in the biosimilar-capable pharmaceutical market through a mandatory exchange of biosimilars in pharmacies. The net cost of replaceable biologics amounted to 4.23 billion euros in 2024, 7.1 percent of the statutory health insurance drug market.
In June 2025, the Federal Joint Committee (G-BA) launched a consultation process to expand biosimilar substitution. The aim is to replace other high-priced biologics with equivalent biosimilars. Studies confirm that such an exchange does not impair the quality of treatment, as the Paul Ehrlich Institute and the Drug Commission of the German Medical Association emphasize.
The WIdO estimates that 2.33 billion euros could be saved with a 70 percent price reduction and 80 percent conversion rate to low-cost biosimilars, and 693 million euros in a more conservative scenario. Since 2006, expiring patents have enabled the market entry of biosimilars that reduce costs without reducing the quality of care.
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