AI revolution in research: CAS SciFinder accelerates scientific breakthroughs

by | Aug 5, 2025 | Research, Sustainability

CAS, a division of the American Chemical Society, has unveiled the next evolution of the CAS SciFinder® platform. By integrating advanced artificial intelligence (AI) optimized for scientific applications with the world’s largest human-curated collection of scientific data, the platform enables researchers to work much faster – and unlock new opportunities for innovation. The move marks the most significant integration of AI into the existing CAS portfolio to date.

The new AI-powered features, in particular the SearchSense search technology, are revolutionizing the way scientists access information. With a single search box, users can make complex queries in natural language. AI-generated summaries quickly filter out relevant results, providing accurate and trustworthy answers. According to CAS, these features increase the efficiency of 93 percent of beta testers. The platform adapts by learning from user activity, personalizing results and optimizing future searches. Data security is guaranteed by a closed system.

Symbolic image. Credits: Tristanmimet/Pixabay
Symbolic image. Credits: Tristanmimet/Pixabay

Another milestone is the first interactive real-time planning tool for retrosynthesis, which reduces the time needed to create synthesis plans from minutes to seconds. This tool provides direct comparisons of real data in synthetic maps, increasing efficiency and encouraging creative approaches to response planning. AI also improves the interpretation of reaction requests and provides the highest precision within the extensive CAS database of over 121 million reactions.

In addition, CAS addresses the need for a better overview in the field of intellectual property. With the IP Connections feature, researchers can efficiently analyze relevant patent and non-patent publications to identify prior art and minimize risks. This AI algorithm optimizes prioritization and reduces time and investment losses.

“Scientific information is complex and traditional AI tools have their limits,” explains Tim Wahlberg, Product Manager at CAS. The combination of high-quality data curated by scientists and advanced AI delivers reliable results. Manuel Guzman, President of CAS, emphasizes: “These innovations accelerate discoveries and bring life-changing solutions to market faster.” The new features will be gradually rolled out to all users over the next two months.

CAS connects global scientific knowledge to enable breakthroughs. More information is available on the CAS SciFinder preview website: Upcoming enhancements to CAS SciFinder

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