New sensor detects scopolamine in beverages within five minutes
Researchers at the Universitat Politècnica de València (UPV) have developed a sensor that detects scopolamine – a substance often used in sexual assault – quickly and sensitively. The system generates an intense fluorescent signal when it comes into contact with the drug and allows detection in less than five minutes.
Scopolamine is difficult to detect with conventional methods, especially in beverages. The new sensor is based on a “molecular cage” that highly selectively interacts with scopolamine and captures it. The reaction releases a fluorescent substance whose light intensity is proportional to the amount of scopolamine. This allows not only the presence but also the concentration to be estimated.

The system does not require complex equipment or specialized personnel and is suitable for police, forensic or preventive operations. It detects extremely small amounts and is suitable for analysis in beverages, urine or saliva.
The team is working on a device with an integrated sensor as well as similar systems for detecting other illegal drugs.
The development involved the UPV’s Interuniversity Research Institute for Molecular Recognition and Technological Development (IDM), the CIBER of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), joint research units of the UPV with CIPF and IIS La Fe, and the University of Jaume I.
The results were published in Angewandte Chemie International Edition.
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