Dresden researchers recommend strategies against cortisone osteoporosis
A team of experts from the University Hospital Carl Gustav Carus Dresden has published recommendations for the prevention and treatment of cortisone-related osteoporosis in the journal Lancet Diabetes & Endocrinology . The guidelines aim to prevent bone fractures in patients who take cortisone preparations for a long time, for example in autoimmune diseases, cancer or after organ transplants.
Cortisone, an indispensable component of therapy for serious diseases, significantly increases bone fragility. More than 50 percent of patients who take more than 7.5 milligrams of prednisolone daily for more than three months suffer fractures, especially of the vertebral bodies, femoral neck or pelvis. The team recommends regular bone density measurements from the start of cortisone therapy, an adequate intake of calcium, vitamin D and protein, and an active lifestyle.
Bisphosphonates or denosumab are used for low to medium fracture risk, bone-building drugs such as romosozumab or teriparatide for high risk. The recommendations, supported by international co-authors, are applicable to different health systems. The research is funded by the Collaborative Research Centre DIONE, which investigates the interactions between the immune system and bone tissue.
Original Paper:
Editor: X-Press Journalistenbüro GbR
Gender Notice. The personal designations used in this text always refer equally to female, male and diverse persons. Double/triple naming and gendered designations are used for better readability. ected.
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