Pharmacies in Germany have discovered quality defects in prescription medicines containing methylphenidate, which are used to treat attention deficit hyperactivity disorder (ADHD). Child-resistant blister packs in particular cause difficulties, as capsules are often difficult or impossible to remove. The Drug Commission of German Pharmacists (AMK) criticizes the lack of user-friendliness and calls for more clearly highlighted information on packaging. Pharmacies play a central role in supporting patients, particularly in the event of supply bottlenecks or changes of preparation, which exacerbate such problems.

The defects concern child-resistant blister packs that are intended to be opened via a perforated tab. In many cases, the foil could not be pulled off as intended, even when strong force was applied. The manufacturer confirmed a quality defect in these cases. In addition, capsules could often only be removed with pointed objects or by tapping, with attempts to push them through the foil often resulting in damage. Such problems jeopardize the correct intake and can impair the effectiveness of the medication, especially with an active ingredient such as methylphenidate, which must be dosed precisely.

Another problem is the unclear labeling of the packaging. Instructions for removal are often overlooked as they are not sufficiently highlighted. The AMK recommends graphic improvements such as borders or high-contrast font colors to avoid misunderstandings. Difficulties often arise when changing preparations due to supply bottlenecks or health insurance requirements for cost reasons. Such changes unsettle patients, especially if the new packaging requires unfamiliar handling.

Pharmacies are the first port of call for problems with medicines. They advise on correct handling, find alternatives in the event of supply bottlenecks and pass on complaints about quality defects. The AMK emphasizes the competence of pharmacists to safeguard the health of patients. Supply shortages, which have increased in recent years, exacerbate the situation as patients have to switch to unfamiliar preparations more frequently. A change of medication can be particularly stressful for ADHD patients who are dependent on stable medication.

The AMK calls for closer cooperation between manufacturers, pharmacies and regulatory authorities in order to improve quality control and stabilize supply chains. The current problems show that the user-friendliness and safety of medicines continue to pose challenges. Pharmacies remain essential to ensure the supply of medicines such as methylphenidate. The AMK plans to hold talks with manufacturers in order to rectify the shortcomings and strengthen patient safety in the long term.

_{Editorial office: X-Press Journalistenbüro GbR}

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